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BPS ▼Human IDO1, His-tag

BPS ▼Human IDO1, His-tag

브랜드 BPS
품명 Human IDO1, His-tag
CAT. NO 71182 분류 Recombinant Protein
규격 50 μg 재고 -
소비자가(₩) 650,000 CAS. NO
온도 -80℃ 위험물
수입발주일 목요일 오후 5시
주의사항
Species: Human
Host Species: E. coli
MW: 46 kDa
Genbank #: NM_002146
Tag(s): N-terminal His-tag
a.a: 2-403(end)
Information:

Human IDO1 enzyme, also known as Indoleamine 2,3-dioxygenase 1, GenBank Accession No. NM_002164, a.a. 2-403(end) with an N-terminal His-tag, expressed in the presence of hemin in an E. coli cell expression system. MW = 46 kDa.

UniProt
P14902
Synonym(s):
Indoleamine 2,3-dioxygenase 1
Assay Conditions:
IDO1 enzyme activity was confirmed using the IDO1 Inhibitor Screening Assay Kit (BPS Cat. #72021) and following the protocol provided with the kit.
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 20% glycerol
Format:
Aqueous buffer solution
Storage / Stability:
>6 months at –80°C.
Application(s):
Useful for studying enzyme kinetics, substrate specificity, and screening inhibitors.
Reference(s):

1. Lob, S. et al., Cancer Immunol. Immunother. 2009; 58(1): 153-157. 
2. Liu, X. et al., Blood. 2010; 115(17): 3520-3530. 
3. Flick, H.E., et al., Int. Nat. J. of Tryptophan Res. 2013; 6: 35-45.

Application Reference(s):
1. Identification and preliminary structure-activity relationships of 1-Indanone derivatives as novel indoleamine-2,3-dioxygenase 1 (IDO1) inhibitors (2017)

Warning(s):
Avoid freeze/thaw cycles. Storing diluted protein is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%).
Scientific Category:
Immunotherapy
Product Type:




Data sheet


Recombinant protein

 

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