ENZO ▼Mdivi-1
ENZO ▼Mdivi-1 |
브랜드 | ENZO | |
---|---|---|---|
품명 | Mdivi-1 | ||
CAT. NO | BML-CM127-0010 | 분류 | inhibitor |
규격 | 1 x 10mg | 재고 | - |
소비자가(₩) | CAS. NO | ||
온도 | -20℃ | 위험물 | |
수입발주일 | 매주 목요일 오후 5시 | ||
주의사항 |
Information
Mdivi-1 is a ive inhibitor of mitochondrial division in yeast and mammalian cells which acts via inhibiting the mitochondrial division dynamin. In cells, Mdivi-1 inhibits apoptosis by inhibiting mitochondrial outer membrane permeabilization. Mdivi-1 causes the rapid (<5 min) reversible and dose-dependent formation of net-like mitochondria in wild-type cells with an IC50= ~10µM. In yeast, time-lapse fluorescence microscopy revealed no detectable mitochondrial division after treatment with Mdivi-1. It inhibits Dnm1 GTPase activity in a dose dependent manner with an estimated IC50 of 1-10µM but is not a general inhibitor of GTPases.
Formula: | C15H10Cl2N2O2S |
MW: | 353.2 |
CAS: | 338967-87-6 |
Purity: | ≥97% (HPLC) |
Identity: | Determined by 1H-NMR. |
Appearance: | White solid. |
Solubility: | Soluble in DMSO (25mg/ml). |
Shipping: | Shipped on Blue Ice |
Long Term Storage: | -20°C
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