Recombinant Protein

TFPI / LACI

TFPI, Anti-convertin, Extrinsic pathway inhibitor, EPI, LACI, TFI, TFPI1

Rabbit

59.2 kDa

aa 39-275

E. coli

E. coli

Greater than 95%

Not Tested

Not Tested

Lyophilized from 100mMNaHCO3, 500mMNaCl, pH8.3, 0.01% sarcosyl, 5% Trehalose.

Reconstitute in 100mM NaHCO3, 500mM NaCl, (pH8.3) to a concentration of 0.1-1.0 mg/ml. Do not vortex.

Store at 4°C for up to 1 month, or aliquot and store at -80°C for up to 1 year. Avoid freeze-thaw cycles.

For research use only.

TFPI / LACI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Uniprot: P10646 NCBI: NM_006287 NP_006278.1