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ALPCO ▼IL-6 (Mouse) ELISA, 96 wells, RUO

ALPCO ▼IL-6 (Mouse) ELISA, 96 wells, RUO

브랜드 ALPCO
품명 IL-6 (Mouse) ELISA, 96 wells, RUO
CAT. NO 61-IL6MS-E01 분류 ELISA kit
규격 재고 -
소비자가(₩) 1,512,000 CAS. NO
온도 4℃ 위험물
수입발주일 매주 수요일 오후 5시
주의사항

Mouse IL-6 ELISA

Interleukin-6 (IL-6) is a multi-functional cytokine that regulates immune responses, acute phase reactions and hematopoiesis and may play a central role in host defense mechanisms. IL-6 is usually not produced constitutively by normal cells, but its expression is readily induced by a variety of cytokines,lipopolysaccharide (LPS) or viral infections. IL-6 is a pleiotropic cytokine produced by a variety of cells. It acts on a wide range of tissues, exerting growth-induction, growth-inhibition, and differentiation respectively, depending on the nature of the target cells. 

IL-6 is involved in: 

- the induction of B-cell differentiation 
- the induction of acute phase proteins in liver cells 
- growth promotion of myeloma/plasmacytoma/hybridoma cells 
- induction of IL-2 and IL-2 receptor expression 
- proliferation and differentiation of T cells 
- inhibition of cell growth of certain myeloid leukemic cell lines and induction of their differentiation to macrophages 
- enhancement of IL-3-induced multipotential colony cell formation in hematopoietic stem cells and induction of maturation of megakaryocytes as a thrombopoietic factor 
- induction of mesangial cell growth 
- induction of neural differentiation of PC 12 cells 
- induction of keratinocyte growth 

The abnormal production of IL-6 was first suggested to be related to polyclonal B-cell activation with autoantibody production in patients with cardiac myxoma. Since then, IL-6 has been suggested to be involved in the pathogenesis of a variety of diseases. Measurement of IL-6 levels in serum and other body fluids thus provides more detailed insights into various pathological situations.

Species: Mouse
Range: 31.3 - 2,000 pg/mL
Sensitivity: 6.5 pg/mL
Sizes: 96 Wells
Sample Types: Cell Culture, Citrate Plasma, EDTA Plasma, Serum
Sample Size: 50 µL

Instructions for Use
Safety Data Sheet

 

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