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BPS ▼	브랜드	BPS
	품명
	CAT. NO	78015	분류
	규격		재고	-
	소비자가(₩)		CAS. NO
	온도		위험물
	수입발주일	목요일 오후 5시
	주의사항

Deion

The 3CL Protease Assay Kit is designed to measure 3CL Protease activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps. 3CL inhibitor GC376 is also included as a positive control.

Note: This kit is for detecting inhibitors of 3CL protease in SARS-CoV-1, the virus that causes SARS disease. To detect inhibitors of 3CL protease in SARS-CoV-2, the virus that causes COVID-19, please use the 3CL Protease, Untagged (SARS-CoV-2) Assay Kit (BPS Bioscience, #78042)

Format

Catalog Number	Component	Amount	Storage
100739	3CL Protease (SARS-CoV-1), MBP-tag, His-Tag	20 µg	-80°C	Avoid freeze/ thaw cycles!
79952	3CL Protease Substrate (10 mM)	25 µl	-80°C
79956	3CL Protease Assay Buffer	25 ml	-20°C
78013	GC376, MW=507.5	50 µg	-20°C
	DTT (0.5 M)	200 µl	-20°C
79685	Black, low binding microtiter plate	1	Room Temp
	Plate sealing film 1	1

Background

Coronaviruses (CoVs) primarily cause multiple respiratory and intestinal infections in humans and animals. Severe acute respiratory syndrome (SARS) is a highly contagious and often fatal viral respiratory illness caused by a coronavirus called SARS-CoV-1. The 3CL protease, also known as Main Protease (Mpro), plays a vital role in processing the polyproteins that are translated from the viral RNA. 3CL Protease inhibitors that can block viral replication are promising potential drug candidates that could be used to treat patients suffering with the coronavirus infection.

Synonym(s)

covid, covid-19, covid19, coronavirus, Severe acute respiratory Coronavirus main protease kit, Mpro kit, 3-CL kit, 3C like protease assay

Instructions for Use

See assay protocol for detailed instructions.

References

1. Morse, J.S., et al., 2020 Chem.Bio.Chem. 21: 730 – 738.
2. Chi-Pang, C., et al., 2011 PLoS ONE 6(11): e27228.

Warnings

Avoid freeze/thaw cycles.

Scientific Category

Coronavirus

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