ENZO ▼Streptozotocin |
브랜드 | ENZO | ||
---|---|---|---|---|
품명 | Streptozotocin | |||
CAT. NO | ALX-380-010-G001 | 분류 | inhibitor | |
규격 | 1g | 재고 | - | |
소비자가(₩) | CAS. NO | |||
온도 | -20℃ | 위험물 | ||
수입발주일 | 매주 목요일 오후 5시 | |||
주의사항 |
Information
Widely used diabetes inducer in rodents. Inhibition of β-cell O-GlcNAcase by streptozotocin is the mechanism that accounts for its diabetogenic toxicity. N-nitroso-containing antibiotic, acting as a nitric oxide (NO) donor and vasorelaxant. Relaxes phenylephrine-contracted aortic rings at 10µM. Potent methylating agent for DNA.
Alternative Name: | Streptozocin, 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose, STZ |
Formula: | C8H15N3O7 |
MW: | 265.2 |
CAS: | 18883-66-4 |
MI: | 14: 8832 |
RTECS: | LZ5775000 |
Purity: | ≥97% (Assay) |
Appearance: | White to pale yellow crystalline solid. |
Solubility: | Soluble in water (nH2O at 102.8mg/ml) or 100% ethanol (200 proof at 0.92mg/ml). |
Shipping: | Shipped on Dry Ice |
Long Term Storage: | -20°C |
Use/Stability: | Because solutions of the compound spontaneously give off NO gas at room temperature, we recommend that solutions be made immediately before use. |
Technical Info/Product Notes: | Solutions of Streptozotocin will spontaneously give off NO gas at room temperature. This NO release is slowed, but not completely stopped at -80°C, and the rate of NO release is also impacted by the solvent used (for example, dissolving Streptozotocin in buffers that contain sodium speeds up NO release).
|