Viromer® YELLOW is designed for the DNA transfection into very challenging cells. This reagent differs from the versatile Viromer® RED in its structural chemistry but follows the same workflow: an Active Endosome Escape to deliver properly nucleic acids of interest into cells with no off-target effects. It allows the mRNA or DNA transfection (plasmids) of cells known as “non-transfectable” so far or only accessible by electroporation. Among others, very high efficacy was reported for human primary chondrocytes, rat primary cardiomyocytes, FAO hepatocytes, as for CHO and HeLa standard cell lines. Viromer® YELLOW is a ready-to-use product for DNA transfection coming with an easy and straightforward protocol, and it is compatible with any culture medium and antibiotics.

CONVINCING RESULTS IN PLASMID TRANSFECTION IN HARD-TO-TRANSFECT CELLS

APPLICATIONS

• protein expression / overexpression
• RNA interference with plasmids encoding for shRNA
• reporter gene assays
• cancer research
• stem cell research
• cell signaling